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Individuals with the following conditions face severe and life-threatening risks and should avoid coffee enemas : Digestive conditions, including Crohns disease, Ulcerative Colitis and Diverticulitis A history of bowel surgery Congestive heart failure Intestinal tumors Gastrointestinal cancer Blood vessel disease Kidney, heart, and liver disease Severe hemorrhoids Abdominal hernias Anemia Allergy to coffee Women who are pregnant or nursing should not undertake a coffee enema

The morphology of FLS was assessed by an inverted microscope with a Leica Qwin System (Leica, Germany)

The perturbation in systemic iron homeostasis was attributed to higher systemic absorption of iron due to enhanced efflux from enterocytes through the basolateral transporter, ferroportin 1

The maximum recommended dose should never be exceeded, and patients should be counselled about seizure warning signs

Contemporary medical, device, and surgical therapies for obesity in adults