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The product information of the Food and Drug Administration (FDA, accessdata.fda.gov) and European Medicine Agency (EMA, ema.europa.eu) on all GLP-1 agonists and SGLT2 inhibitors were searched for additional data

: The 12-week fixed course reduces treatment burden compared to longer infusion regimens, which matters significantly for a patient population often managing concurrent thyroid disease and endocrine follow-up

It lowers blood glucose levels by increasing insulin secretion and reducing the amount of sugar produced in the liver

Overview of Study 5 and Study 6 The efficacy of ZEPBOUND for moderate to severe obstructive sleep apnea (OSA) (apnea-hypopnea index [AHI] 15) in patients with obesity (BMI 30 kg/m2) was evaluated in a master protocol clinical trial (NCT05412004) that included two randomized, double-blind, placebo-controlled trials (Study 5 and Study 6) of 52 weeks duration