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Although adults are more likely to smoke than to vape, the share of 18- to 29-year-olds who smoke traditional cigarettes has fallen over time

The areas of the brain involved in higher cognitive processes such as planning or impulse control take until the age of 20 or beyond to complete development, and exposure to nicotine will interfere with that, says Huib Mansvelder, professor of neurophysiology at the Vrije Universiteit in Amsterdam

Aversion to nicotine is regulated by the balanced activity of Beta4 and Alpha5 nicotinic receptor subunits in the medial Habenula

However, with regular daily smoking, those trace THC amounts can accumulate in body fat over time, and a sensitive drug test may flag positive even at these trace levels