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154 The relatively low mechanical stress (about 45 Pa) derived by the ECM can stimulate the stem cell signaling pathway via the cytoskeleton/AIRE axis by activating the integrin beta 1/3 receptor, while excessive mechanical stress (~450 Pa) induces quiescence in BCSCs dependent on DDR2/STAT1/P27 signaling, which may explain conflicting results observed in previous individual studies

Louise I feel that I had a really easy run in my first trimester, compared to my friends who werent in Wild Nutrition and I feel I must credit some of that to the extra energy and vitamins I got from the pregnancy supplements