Their primary mechanisms of action include: Stimulating insulin secretion in a glucose-dependent manner (reducing hypoglycaemia risk) Suppressing glucagon release when blood glucose is elevated Slowing gastric emptying, which prolongs satiety Acting on appetite centres in the brain to reduce food intake Common GLP-1 medicines available in the UK include semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and dulaglutide (Trulicity)
Price snapshot : List price: Zepbound: $1,060 / month Mounjaro: $1,112 / month With insurance: Zepbound: $25$150 / month (varies by plan) Mounjaro: $25$150 / month (varies by plan) Without insurance (cash): Zepbound: $299$449 / month (with manufacturer direct-pay ) Mounjaro: $1,056$1,150 / month Tirzepatide cost: News and changes for 2026 Tirzepatide pricing has shifted quite a bit since 2025, with several key changes affecting how much people pay
These results established semaglutide's FDA-approved status for chronic weight management
Youre losing fat and gaining muscle Exercise changes your body composition
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