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A new paper in Lancet Diabetes & Endocrinology gives us reasons for both caution and reassurance

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Individual variation is substantialsome patients experience minimal symptoms while others need 810 weeks for full tolerance development

Reviews note that staff typically respond quickly, even on weekends, though some patients report occasional delays during high-volume periods

MetS has also been identified as the cause of microvascular rarefaction characterized by reduced microvascular density and endothelial dysfunction [9, 34]