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Congenital dermal melanocytosis can occur sporadically or, in cases of extensive and large lesions, can be associated with inborn errors of metabolism, such as mucopolysaccharidosis, gangliosidosis, Niemann-Pick disease, Hunter syndrome, and mannosidosis [5963]

Since the gut is subject to daily wear and tear from food, bacteria, and toxins, maintaining a healthy turnover of gut cells is essential

Disclosures Disclosure forms, as provided by each author, are available with the online version of the article at Author Contributions Conceptualization: Yuki Sugiura, Motoko Yanagita

Available from: and OConnor Christina

The term has emerged in informal community discussion as a shorthand for "the third generation of GLP-class peptides" specifically retatrutide, which acts on three receptors (GLP-1, GIP, and glucagon)