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The magnitude of GLP-1 enhancement achievable through diet differs substantially from pharmaceutical interventions, and patients should understand these distinctions clearly

Genetic variants in GLP1R and GIPR pathways partly explain this variation

Diabetes Res Clin Pract 171:108610

The greatest changes in NCV (at 12 months) were observed in the sensory sural nerve (+5.7 m/sec in the LAC group vs +1.0 m/sec in the placebo group), sensory ulnar nerve (+2.9 vs +0.1 m/sec, respectively) and motor peroneal nerve (+2.7 vs 0.2 m/sec), whereas the greatest changes in amplitude were recorded in the motor peroneal nerve (+2.2 vs +0.1 mV)