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(152) reported an increase in daily urine levels of 8-hydroxy-2-doxyguanosine (8-OHdG, a marker of DNA damage) in AD patients, which points to oxidative stress

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In contrast, the SLC19A3 protein is shown to localize specifically to the apical (brush border) membrane (108)

Overall, our findings suggest that both intrinsic and extrinsic factors contribute to CAR T cell functionality post-infusion, including a cross-talk between microenvironmental nutrients and the CAR T cell immunometabolic state in patients