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In 2023, the agency reclassified BPC-157 and 18 other manmade peptides as Category 2 Bulk Drug Substances, effectively barring compounding pharmacies from producing them, citing safety concerns and insufficient information on their effects in humans

These include localised or systemic infections from non-sterile manufacturing, severe toxicity from chemical contaminants, unpredictable side effects from incorrect dosing, and rapid drug degradation caused by a total lack of temperature-controlled shipping and storage

The appeal of direct neck excision lies in the visible outcome it creates and the simplicity of the in-office procedure

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