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Crucially, FOXO4 knockdown significantly reduced the viability of senescent TM3 Leydig cells and substantially increased their rate of apoptosis

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These molecules are the life-blood of cellular metabolism

Many studies report non-random exposure to mycotoxins, which could be influenced by dietary habits, socioeconomic status, or geographical location (Abia et al

Features of SIPS include increased senescence-associated -galactosidase (SA--Gal) activity, appearance of senescence-associated heterochromatin foci (SAHF), cell growth arrest, and increased expression of senescence-associated genes 11,34