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Obesity significantly increases loading forces on the knees, hips, ankles, and spine, accelerating cartilage degradation and contributing to osteoarthritis development and progression

PlexusDx designs dose schedules that balance therapeutic weight loss against metabolic stressyour dose may need to go up, but your price won't, keeping treatment affordable as your therapy advances

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Conversely, patients with minimal adverse effects and inadequate therapeutic response may undergo more rapid titration under careful medical supervision