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Findings: Animal models showed that increased GH levels promoted protein synthesis and lean tissue maintenance

Neutralizes free radicals via the antioxidant properties of some peptides, reducing damage to cellular DNA

Both forms offer potent tools in the fight against obesity, with distinct advantages and potential drawbacks

Specific pathways affected include TGF-beta superfamily signaling, Wnt signaling, antioxidant defense (including superoxide dismutase, glutathione S-transferases, and thioredoxin reductase), and DNA repair mechanisms

While GLP-1 therapies offer substantial benefits through well-established mechanisms, their influence on cortisol levels remains unclear