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Like BPC-157, its mechanisms operate independently of semaglutide's appetite and glucose effects

doi: 10.3389/fnut.2025.1701661 Received 08 September 2025 Revised 10 November 2025 Accepted 04 December 2025 Published 05 January 2026 Volume 12 - 2025 Edited by Emanuele Micaglio, IRCCS San Donato Polyclinic, Italy Reviewed by Runzhe Xu, University of Texas Southwestern Medical Center, United States Husain Alkhaldy, King Khalid University, Saudi Arabia Updates Copyright 2026 de Carvalho, Akamine, Di Pietro, Frana, Oliveira and Lopes

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Mechanism Differentiation: Multi-Pathway Support vs Receptor-Specific Amplification Cerebrolysin functions as a neurotrophic factor mixture containing brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), ciliary neurotrophic factor (CNTF), and glial cell line-derived neurotrophic factor (GDNF) analogs alongside free amino acids that support protein synthesis