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Canonical GPX4/glutathione (GSH) defense axis The canonical axis defending against ferroptosis is centered on the GPX4/GSH system (26)

DECLARATIONS Authors contributions Performed literature search, review writing, data analysis, and interpretation: Ding M Made significant contributions to the conception, design, and revision of the manuscript: Luo Y Proposed the rationale and framework of review, provided guidance for manuscript design: Ji L Availability of data and materials Not applicable

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Always follow your healthcare provider's instructions on how to use Semaglutide